Host–pathogen interactions and genetic tools for resistance to porcine reproductive and respiratory syndrome virus

Table of contents 1 Introduction 2 Porcine reproductive and respiratory syndrome and porcine respiratory disease complex 3 The lung macrophage as the target for porcine reproductive and respiratory virus infection 4 CD163: a functional marker for anti-inflammatory M2 macrophages and a receptor for porcine reproductive and respiratory virus 5 The porcine reproductive and respiratory syndrome Host Genetics Consortium and the search for host genes affecting the response to porcine reproductive and respiratory syndrome infection 6 The WUR marker and its association with guanylate binding protein 5 7 The interplay between porcine reproductive and respiratory syndrome virus, M1 and M2 macrophages, CD163 and guanylate binding protein 5 in the onset and recovery from acute respiratory disease 8 Porcine reproductive and respiratory syndrome resistance through modification of CD163
9 Genetic association between the pig genome and porcine circovirus type 2 and swine influenza A virus 10 Conclusion and future trends 11 Where to look for further information 12 References