Advances in the development and use of vaccines for prevention of endemic diseases in pigs

Code: 9781801466905
Publication date: 31/10/2022
Extent: 36 pages

Contributions by: Enric Mateu, Universitat Autònoma de Barcelona, Spain; Ivan Díaz, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB) and OIE Collaborating Centre for the Research and Control of Emerging and Re-Emerging Swine Diseases in Europe (IRTA-CReSA), Spain; and Gerard Martín-Valls, Universitat Autònoma de Barcelona, Spain

Chapter synopsis: The current trend of pig/swine production towards intensive industrialised production creates a window of opportunity for pathogens to spread between and within farms. The main focus of vaccination are gilts and weaners. For gilts the challenge is to acclimatise them before entering the breeding stock while, for piglets, the challenge is to immunise them in the presence of maternally derived antibodies (MDA). Vaccination remains a powerful tool to prevent infectious diseases but faces difficulties in dealing with endemic disease. The development of newer vaccines and adjuvants, as well as a better knowledge of pig immunology and of the epidemiology of diseases, may help to improve our approaches to vaccination. This chapter reviews the current use of vaccines and vaccination programs in controlling endemic diseases in pigs. It also discusses the future of vaccines and vaccination in pigs.

DOI: 10.19103/AS.2022.0103.13
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Table of contents 1 Introduction 2 How infectious diseases become endemic in pig farms 3 Target populations and the dynamics of infection in endemically infected pig herds 4 The aims of vaccination in endemically infected farms and potential vaccine efficacy 5 The immunological basis of vaccination 6 Vaccine types and development 7 Limitations of vaccines and ways to overcome them 8 Conclusion and future trends 9 Where to look for further information 10 References

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